ficolin-a enhances inhibition of the c-terminal 19 kda region of merozoite surface protein-1 of plasmodium berghei using test in vivo.

Ficolin-A Enhances Inhibition of the C-Terminal 19 kDa Region of Merozoite Surface Protein-1 of Plasmodium berghei Using Test In Vivo

BACKGROUND Malaria remains a serious public health problem with significant morbidity and mortality. This study was conducted to identify whether ficolin-A could play an active role of against malaria infection. METHODS The function of ficolin-A was analyzed in mouse model. The open reading frame of ficolin-A was cloned from the liver of new born C57BL/6 mice by RT-PCR and then inserted into ...

Parasite-Specific Antibodies Protein-1-Specific Antibodies but Not Whole Region of Merozoite Surface Maternally Derived 19-kDa C-Terminal Antibody Responses in Neonatal Pups by Merozoite Surface Protein-1-Specific Inhibition of 19-kDa C-Terminal Region of

بررسی گلیکوزیلاسیون آنتی ژن c-terminal msp1 (c-terminal merozoite surface protein) در پلاسمودیوم فالسیپاروم

مالاریا یکی از بیماری های مهم انگلی در کشورهای گرمسیری دنیا است. پلاسمودیوم فالسیپاروم انگل تک یاخته ای است که تب سه یک بدخیم را ایجاد می کند. آنتی ژن های پلاسمودیوم فالسیپاروم در سطح انگل یا در سطح سلول های آلوده ،کاندیداهای عمده جهت تولید واکسن می باشند، مانند: msp 1 و msp2 . کربوهیدرات های متصل به پروتئین های انگل مالاریا بعنوان اپی توپ های آنتی ژنیک مطرح بوده و بوسیله سیستم ایمنی میزبان تشخ...

analysis of plasmodium vivax merozoite surface protein-1 gene sequences

the emergence of plasmodium vivax in dashte moghan in northwestern iran has become a major concern for iranian's health officials. knowledge of genetic make up of the p. vivax populations in this area would give us an insight into the origin of the prevalent infections and the possible routes they are introduced. this paper reports the analysis of a variable region between the two interspecies ...

Naturally acquired antibody responses to the C-terminal region of merozoite surface protein 1 of Plasmodium vivax in Korea.

We expressed a protein in Saccharomyces cerevisiae in order to evaluate the humoral immune responses to the C-terminal region of the merozoite surface protein 1 of Plasmodium vivax. This protein (Pv200(18)) had a molecular mass of 18 kDa and was reactive with the sera of individuals with patent vivax malaria on immunoblotting analysis. The levels of immunoglobulin M (IgM) and IgG antibodies aga...

C-terminal polymorphism of Plasmodium falciparium merozoite surface protein-1 (MSP-1) from Tak Province, Thailand.

This study was undertaken to ascertain the extent of polymorphism in the C-terminal region of Plasmodium falciparum merozoite surface protein (MSP-1) from 119 malaria patients in Tak Province on the western border of Thailand, who were admitted to the Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. P. falciparum infection was confirme...